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SummaryР”В¬hronically elevated blood sugar levels are common in people with uncontrolled diabetes and can have serious health effects. Therefore, no conclusions could be made about the effects of Cordyceps on kidney function in humans with chronic kidney disease. The authors of the review stated that many of the studies were low quality. However, these results arenРІР‚в„ўt conclusive. In a review of 22 studies including 1,746 people with chronic kidney disease, those who took Cordyceps supplements experienced improved kidney function ( 31). Some evidence suggests that they may also protect against kidney disease, a common complication of diabetes. In several studies in diabetic mice, Cordyceps have been shown to decrease blood sugar levels ( 28, 29, 30). Interestingly, Cordyceps may keep blood sugar levels within a healthy range by mimicking the action of insulin.

Therefore, itРІР‚в„ўs important for people with diabetes to make sure their blood sugar levels are well controlled. Over time, having too much glucose in the blood can cause serious health problems. When your body does not produce enough insulin or respond well to it, glucose cannot enter the cells, so it stays in the blood. However, these effects have not been shown in humans, and more research is needed.Р”В¬ordyceps contain a special type of sugar that may help treat diabetes.Р”Вiabetes is a disease in which the body either does not produce or respond to the hormone insulin, which normally transports the sugar glucose into your cells for energy. Test-tube and animal studies suggest Cordyceps may have the potential to treat cancer, as well as some side effects of cancer treatments.

The effects of Cordyceps on leukopenia and tumor growth in humans is unknown, so health experts canРІР‚в„ўt currently draw conclusions. However, itРІР‚в„ўs important to note that these studies were performed in animals and test tubes, not humans. These results suggest the fungi may help reduce complications associated with some cancer treatments. Interestingly, Cordyceps reversed the leukopenia. One study tested the effects of Cordyceps on mice that developed leukopenia after radiation and treatments with Taxol, a common chemotherapy drug ( 27). Not to be confused with the cancer leukemia, leukopenia is a condition in which the number of white blood cells (leukocytes) decreases, lowering the bodyРІР‚в„ўs defenses and increasing the risk of infection ( 26). Studies in mice have also shown that Cordyceps have anti-tumor effects on lymphoma, melanoma and lung cancer ( 22, 23, 24, 25).Р”В¬ordyceps may also reverse the side effects associated with many forms of cancer therapy.

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In test-tube studies, Cordyceps have been shown to inhibit the growth of many types of human cancer cells, including lung, colon, skin and liver cancers ( 18, 19, 20, 21). Researchers believe the fungi may exert anti-tumor effects in several ways. SummaryР”В¬ordyceps have been shown to improve measures of exercise performance in older and younger adults, but not in well-trained athletes.Р”В¬ordycepsРІР‚в„ў potential to slow the growth of tumors has generated significant interest in recent years. However, the current research suggests Cordyceps are not effective at improving exercise performance in trained athletes ( 7, 8).

One study also tested the effects of a Cordyceps-containing mushroom blend on exercise performance in younger adults ( 6).Р”Р„fter three weeks, participantsРІР‚в„ў VO2 max had increased by 11%, compared to a placebo. While researchers found no change in VO2 max in either group, participants given CS-4 improved other measures of exercise performance. In a similar study, 20 healthy older adults received either 1 gram of CS-4 or a placebo pill for 12 weeks ( 5). VO2 max is a measurement used to determine fitness level ( 4). Participants received either 3 grams per day of a synthetic strain of Cordyceps called CS-4 or a placebo pill for six weeks.Р”В«y the end of the study, VO2 max had increased by 7% in participants who had taken CS-4, while participants given the placebo pill showed no change ( 3). In one study, researchers tested their effects on exercise capacity in 30 healthy older adults using a stationary bike. This may improve the way your body uses oxygen, especially during exercise ( 1, 2). Cordyceps are thought to increase the bodyРІР‚в„ўs production of the molecule adenosine triphosphate (ATP), which is essential for delivering energy to the muscles.